1. The Grain of Salt
On October 14, 2024, the Royal Swedish Academy of Sciences awarded the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel to Daron Acemoglu, Simon Johnson, and James A. Robinson for "studies of how institutions are formed and affect prosperity." At the center of the global fanfare was a single, legendary empirical paper: their 2001 article in the American Economic Review, "The Colonial Origins of Comparative Development."
For more than two decades, that paper has been taught in virtually every graduate economics sequence on the planet. It is the canonical template for how to use a creative historical natural experiment to tame the monster of macroeconomic endogeneity. Yet if you set aside the press releases and read the Nobel Committee's official 57-page Scientific Background document, you encounter an extraordinary admission buried quietly on page 18:
"The actual IV-estimate should thus be taken with a grain of salt. Nevertheless, the evidence presented by Acemoglu, Johnson, and Robinson strongly suggests that the type of institutions implemented by the colonizers is a key mechanism driving the relationship between contemporary GDP and the conditions at colonization."
In the polite, guarded dialect of Swedish academic committees, writing that a laureate's headline regression estimate should be "taken with a grain of salt" is the intellectual equivalent of setting off a siren. The committee did not stumble upon this caveat by accident. They were looking squarely at twenty-three years of blistering methodological warfare.
They knew about Jeffrey Sachs's demonstration that tropical disease ecology directly suppresses modern agricultural productivity and life expectancy, obliterating the exclusion restriction. They knew about Edward Glaeser, Rafael La Porta, Florencio Lopez-de-Silanes, and Andrei Shleifer's proof that European settlers brought their own human capital, literacy, and skills, not just parchment constitutions. They knew about David Albouy's devastating archival discovery that for 36 of the 64 countries in the baseline sample, historical mortality rates had been imputed from military campaigns hundreds of miles away. And they knew that once those contaminated observations are excised, the first-stage $F$-statistic collapses, plunging the two-stage least squares estimator into the abyss of weak instrument bias.
By the textbook standards of modern applied microeconometrics—the Credibility Revolution codified by Guido Imbens and Joshua Angrist's 2021 Nobel Prize—Acemoglu, Johnson, and Robinson's (AJR) settler mortality instrument is not merely fragile. It is, in the infamous off-the-record description popularized by academic blogs, an econometric dumpster fire.
Which brings us to the central epistemic puzzle: Why did the Nobel Committee give it such immense weight anyway?
To answer that question, one has to look past the mechanical arithmetic of two-stage least squares and examine what economic science actually looked like in the late 1990s, the profound difference between a point estimate and a paradigm shift, and how a flawed empirical sledgehammer cleared the ground for a revolution that reshaped modern social science.
2. The 1990s Deadlock: Geography vs. Culture
To understand the impact of AJR (2001), one must remember the intellectual paralysis that gripped development economics thirty years ago. Across the globe, the income gap between the richest and poorest nations was vast and widening: citizens of the United States, Switzerland, and Sweden enjoyed living standards thirty to fifty times higher than those in Mali, Bolivia, or Bangladesh. Yet macroeconomics had no rigorous, causal answer for why.
The discipline was split into two dominant, deeply deterministic camps:
Geography as Destiny
Championed by Jeffrey Sachs, Jared Diamond (Guns, Germs, and Steel), and intellectual heirs to Montesquieu. Nations near the equator are poor because of harsh tropical climates, leached soils, severe agricultural pest burdens, and hyper-endemic diseases like malaria and schistosomiasis. Distance from major oceanic trade corridors and coastal ports permanently depresses gains from specialization.
Culture as Destiny
Championed by David Landes (The Wealth and Poverty of Nations) and rooted in Max Weber's thesis on the Protestant Ethic. Wealth reflects deep, slow-moving cultural traits: social trust, individualism, respect for commerce, and cognitive thrift. Extractive poverty in southern Europe, Latin America, or Africa was seen as the cultural residue of hierarchical empires, clientelism, or fatalistic worldviews.
Both theories shared a dark, conservative policy implication: fatalism. A country cannot change its geographic latitude. A country cannot alter its annual rainfall or move its tectonic plate closer to Western Europe. And cultural values evolve across centuries, if at all. If tropical geography or civilizational culture dictated national wealth, international development policy was essentially hospice care.
There was, of course, a third voice. Douglass North (who shared the 1993 Nobel Prize with Robert Fogel) had insisted for decades that institutions—"the rules of the game in a society, or, more formally, the humanly devised constraints that shape human interaction"—were the fundamental engine of growth. Secure private property rights, independent courts, constraints on expropriation, and contract enforcement allow citizens to invest capital without fearing that predatory sovereigns will confiscate the surplus tomorrow.
The trouble with North's institutional thesis was not its intuition; it was its econometrics. In cross-country data, institutional quality and GDP per capita were furiously correlated ($r \approx 0.7$ to $0.8$). But correlation told economists nothing about causality:
Rich societies have pristine property registries, independent judiciaries, and computerized cadastral databases. But do good institutions make societies rich, or do rich societies simply buy better courts, police, and bureaucrats because justice is a normal luxury good?
Worse, both GDP and legal institutions could be joint consequences of unobserved third variables ($U$): historical human capital, early industrial infrastructure, or institutional memory. Running an ordinary least squares (OLS) regression of GDP on property rights was an exercise in pure confounding.
Economists were trapped. If you regressed modern income on modern institutions, critics rightly cried reverse causality. If you pointed to the tropics, geographic determinists claimed biology and climate explained everything. The debate was paralyzed.
3. The Architecture of the Instrument
Acemoglu, Johnson, and Robinson entered this deadlock with an audacious idea: they would find an exogenous historical shock that determined the kind of institutions Europeans established centuries ago, but that had no direct bearing on economic productivity today.
Their insight began with colonial history. European imperial expansion from 1500 onward was not uniform. In some parts of the world—the United States, Canada, Australia, and New Zealand—Europeans migrated in massive numbers, brought their families, and established permanent settlements. Because they planned to live there, these settlers demanded European-style legal protections: secure property rights, equality before the law, and assemblies that checked the arbitrary power of the crown (what AJR termed "institutions of private property" or inclusive institutions).
In other parts of the world—the Congo basin, the Caribbean sugar islands, the silver mines of Potosí, and coastal West Africa—Europeans did not intend to settle. Instead, colonial powers erected "extractive states." The objective was simple: extract maximum rents, minerals, rubber, and agricultural commodities at minimum cost, using forced indigenous or enslaved labor. The legal architecture was deliberately designed to concentrate power in the hands of a tiny colonial elite and suppress economic rights for the broad population.
What determined which strategy a colonial power chose? AJR's answer was the disease environment faced by the early European colonizers:
Where European soldiers, sailors, and colonial administrators were wiped out by virulent strains of malaria and yellow fever—diseases to which Europeans had developed no biological resistance—mortality rates routinely exceeded 100 to 500 per thousand per year. Europeans knew these places as the "White Man's Grave." Settlers refused to go. Instead, European states set up extractive slaving forts and plantations.
Crucially, AJR argued that institutions persist: once established, the machinery of an extractive state does not magically vanish upon independence. When post-colonial leaders took over, they found an apparatus built for despotism—centralized monopolies, weak judiciaries, disenfranchised populations—and used it to enrich their own ruling coalitions.
Mathematically, AJR set up the two-equation instrumental variables model across a cross-section of 64 former colonies:
The empirical results appeared sensational. In the first stage, the log of historical settler mortality ($\ln M$) strongly predicted modern protection against expropriation risk ($\pi = -0.61$, $t = -4.3$). In the second stage, the estimated return to institutional quality was massive ($\hat{\beta}_{\text{2SLS}} \approx 0.94$).
Most strikingly, when AJR added control variables ($\mathbf{X}_i$)—distance from the equator (latitude), malaria ecology, temperature, humidity, continent dummies, and British legal origin—institutions remained robustly significant, while latitude and geographic variables dropped to zero.
It was hailed as an intellectual triumph. The paper appeared to prove, with modern econometric finality, that institutions were the fundamental cause of wealth, and that geography was merely a passive backdrop.
Then the forensic accountants arrived.
4. The Multi-Channel Breach
The validity of any instrumental variable hinges on the exclusion restriction: the instrument $Z$ (historical settler mortality) must affect the outcome $Y$ (modern GDP per capita) only through its effect on the endogenous regressor $D$ (institutions). In causal DAG notation, there can be no direct arrow from $Z$ to $Y$, and no unblocked backdoor path:
Almost immediately, development economists realized that settler mortality is not an excludable historical lightning strike. It is an ecological footprint.
The Sachs Ecological Critique
In a series of blistering critiques, Jeffrey Sachs (2001, 2003) pointed out that European settlers did not die of arbitrary bureaucratic illnesses. They died primarily of Plasmodium falciparum malaria and yellow fever, carried by tropical mosquito vectors (chiefly Anopheles gambiae).
That same disease ecology did not disappear when colonial flags were lowered:
- Infant Development and Cognitive Burden: Chronic endemic malaria, hookworm, and parasitic infections inflict severe anemia, cognitive deficits, and stunting during critical early childhood windows, directly suppressing adult labor productivity.
- Agricultural Yields: Tropical soils and parasite-heavy ecologies suffer from severe agricultural vulnerabilities (crop blights, cattle-killing tsetse flies) that depress agricultural total factor productivity.
- Direct Foreign Investment and Trade: High disease environments deter foreign tourism, skilled migrant labor, and direct physical capital investment today, entirely independent of judicial expropriation risk.
If historical settler mortality is simply a proxy for permanent tropical biogeography, then $Z$ feeds directly into modern poverty ($Y$) via health and biology. In regression terms, $\operatorname{Cov}(Z, \varepsilon) \neq 0$, and the 2SLS estimator is fundamentally contaminated.
The Glaeser Human Capital Critique
In 2004, Edward Glaeser, Rafael La Porta, Florencio Lopez-de-Silanes, and Andrei Shleifer published "Do Institutions Cause Growth?" in the Journal of Economic Growth, taking aim from an entirely different angle.
They asked a deceptively simple historical question: What did European settlers actually bring with them?
When Europeans decided to settle in Boston, Melbourne, or Wellington rather than Freetown or Lagos, they did not just bring John Locke's treatises and Common Law statutes. They brought themselves. They brought high literacy rates, numeracy, technical engineering know-how, European scientific techniques, and administrative traditions:
Where Europeans settled, they established universal schools and universities. Where they did not settle, they barred the native population from education. Glaeser et al. demonstrated that historical settler mortality predicts modern schooling and human capital just as strongly as it predicts property rights.
When human capital is included in growth regressions, human capital predicts growth, while formal institutional constraints become insignificant. Was it property rights that drove development, or was it the literacy, culture, and human capital of the settlers? Settler mortality cannot separate the two.
5. The Albouy Excavation
If the exclusion restriction was bruised by Sachs and Glaeser, the empirical data itself was about to take a direct hit.
In 2004, a graduate student at UC Berkeley named David Albouy began attempting to replicate AJR (2001) for a term paper. What began as a routine replication exercise turned into an eight-year scholarly odyssey that culminated in a devastating 2012 critique in the American Economic Review: "The Colonial Origins of Comparative Development: An Empirical Investigation: Comment."
Albouy dug into the historical citations underlying AJR's settler mortality dataset (principally Philip Curtin's 1989 and 1998 histories of military mortality, and Hector Gutierrez's 1986 demographic studies). What he uncovered shocked the econometric community:
The details of the imputation were forensic dynamite:
- Borrowing Across Continents: Settler mortality for Mali was assigned from French soldiers stationed in Senegal or marching along the Gambia river. Several Sub-Saharan African countries were assigned identical mortality rates based on military expeditions in distant territories.
- Soldiers on Campaign vs. Civilian Settlers: A large portion of AJR's mortality data did not reflect civilian settlers building homesteads; it reflected European soldiers on active wartime campaigns. Soldiers marching through swamps during military conquests succumbed to dysentery, typhus, and yellow fever at rates four to ten times higher than soldiers stationed in peacetime barracks, let alone civilian colonists who had built dwellings and acclimatized.
- Latin American Imputations: For much of South America, AJR had virtually no civilian settler data. Instead, mortality was imputed from military detachments or Catholic bishop records, often extrapolating a single garrison's fever spike across entire nations.
Albouy showed that when you clean the data—dropping the 36 imputed observations, controlling for whether mortality came from wartime campaigns, or clustering standard errors properly—the first-stage relationship between settler mortality and expropriation risk breaks down completely.
In their 2012 reply, Acemoglu, Johnson, and Robinson mounted a spirited defense. They argued that military mortality was the best available proxy for the general disease environment, that their core results survived if you dropped African nations entirely (eliminating the most contested data points), and that capping extreme mortality rates at 250 per thousand preserved a negative slope. But the aura of an airtight, pristine natural experiment was permanently shattered.
6. The Weak Instrument Pathology
The Albouy critique had an even deeper econometric consequence: it pushed AJR (2001) directly into the crosshairs of the weak instrument revolution.
Around the same time AJR was published, econometricians James Stock, Jonathan Wright, and Motohiro Yogo (2002) were developing the modern theory of weak instruments. In an instrumental variable regression, the first-stage $F$-statistic tests the null hypothesis that the instrument has zero explanatory power ($\pi = 0$). Stock and Yogo established the famous rule of thumb: an $F$-statistic must exceed 10 (and in many settings, 15 to 20) to ensure that two-stage least squares bias is less than 10% of OLS bias.
Why does instrument strength matter so profoundly? Because of the mathematical structure of the 2SLS probability limit:
Look carefully at the denominator: $\operatorname{Cov}(Z, D)$. If the instrument is strong, $\operatorname{Cov}(Z, D)$ is large, and a tiny exclusion restriction violation ($\operatorname{Cov}(Z, \varepsilon) \approx 0$) produces only a negligible bias.
But if the instrument is weak—meaning $\operatorname{Cov}(Z, D) \to 0$—the denominator shrinks toward zero. Any microscopic violation of the exclusion restriction, any faint ecological leak via malaria, any small human capital spillover, is divided by zero and magnified toward infinity:
In finite samples with a weak instrument, 2SLS is not just inefficient; it is biased in the exact same direction as OLS, but with wildly understated standard errors that produce disastrously false confidence intervals.
When Albouy and later researchers (such as Samuel Bazzi and Michael Clemens in their famous 2013 AER paper "Blunt Instruments") re-evaluated AJR's specifications with robust controls, the first-stage $F$-statistic plummeted well below 10, often dropping into the danger zone between 1 and 4.
When an instrument is weak, standard Wald confidence intervals ($\hat{\beta} \pm 1.96 \cdot \text{SE}$) are completely invalid because the sampling distribution of $\hat{\beta}_{\text{2SLS}}$ is non-normal and Cauchy-tailed.
To obtain valid inference, econometricians must compute Anderson-Rubin (AR) confidence sets, which remain valid regardless of instrument strength. When researchers computed Anderson-Rubin confidence sets for AJR's specification, the confidence intervals exploded: they spanned from negative numbers all the way to positive infinity ($[-\infty, +\infty]$). The data simply could not reject the hypothesis that institutions had zero effect, or even a negative effect!
7. The Measurement Trap
There was one final, conceptual critique: What was the variable $D$ that AJR actually measured?
AJR used the "Protection Against Expropriation Risk" index, published by Political Risk Services in the International Country Risk Guide (ICRG), averaged between 1985 and 1995.
Glaeser et al. (2004) pointed out that this metric does not measure institutions at all. It measures an ex-post outcome:
Durable Rules of the Game
Constitutional constraints, independent judicial tenure, bicameral veto points, and electoral rules. These are structural, slow-moving procedural barriers that prevent any leader from acting as a despot.
Policy Choices & Investor Sentiment
A subjective survey of whether foreign investors think their assets will be seized this decade. An enlightened dictator (such as Lee Kuan Yew in Singapore or Park Chung-hee in South Korea) can protect property rights by executive whim without establishing inclusive institutions.
When researchers replaced ICRG expropriation risk with objective constitutional constraints—such as executive constraints from the Polity IV dataset—the statistical relationship with settler mortality weakened further. If the instrument was predicting policy choices by autocrats rather than deep constitutional structures, the theoretical link between colonial settlement and modern democracy was severed.
8. Interactive Lab: Weak IV & Exclusion Blowup
To build an intuitive grasp of how weak instruments and exclusion leaks interact to destroy causal estimates, explore the interactive simulator below. Adjust the first-stage strength (the $F$-statistic) and the magnitude of the exclusion violation ($\operatorname{Cov}(Z, \varepsilon)$) to observe how the estimated 2SLS treatment effect explodes relative to the true effect.
9. The Triangulation Defense: Reversal of Fortune
We now return to the central paradox of this essay. The Nobel Committee knew all of this. They read Albouy; they cited Glaeser; they acknowledged Sachs; they warned that the point estimate should be taken with a grain of salt.
Why, then, did they honor Acemoglu, Johnson, and Robinson?
The first reason is that AJR's case for institutions never rested solely on the settler mortality instrument. In the popular imagination, AJR (2001) is remembered for the settler mortality scatterplot. But in the architecture of their scholarship, AJR (2001) was only the first half of a dual masterpiece.
The second half was published one year later in the Quarterly Journal of Economics: "Reversal of Fortune: Geography and Institutions in the Making of the Modern World Income Distribution" (AJR, 2002).
The Reversal of Fortune paper presented a historical pattern so striking that pure geographic determinism could not explain it:
| Region / Colony | Prosperity in 1500 (Urbanization & Population Density) | Colonial Strategy | Prosperity Today (GDP per Capita) |
|---|---|---|---|
| Mesoamerica & Andes (Aztecs, Incas) | Very High: Dense urban centers, sophisticated agricultural terraces, complex states. | Extractive: Encomienda, mita forced labor, silver extraction for Spanish Crown. | Middle / Low: Lower-middle income, persistent inequality, weak property protections. |
| Mughal India & Bengal | Very High: Global textile manufacturing center, dense cities, high wealth. | Extractive: British East India Company monopoly concessions, land tax extraction. | Developing: Long struggle with post-colonial poverty and state capacity. |
| North America (US & Canada) | Very Low: Sparsely populated hunter-gatherer bands, virtually no urban centers. | Inclusive Settler: Smallholder agriculture, land grants, local assemblies, rule of law. | Highest in World: Frontier technological innovator, high living standards. |
| Australasia (Australia & NZ) | Very Low: Nomadic populations, zero pre-1500 urban density. | Inclusive Settler: Broad voting rights, secret ballot, secure land ownership. | Highest in World: High median wealth, strong institutional stability. |
Notice what happened: The places that were richest and most urbanized in 1500 became the poorest, while the places that were poorest and most barren became the richest.
This reversal is an insurmountable problem for pure geographic theories of development:
Geography is fixed. The soil of the Valley of Mexico did not suddenly change in 1800. The climate of Massachusetts did not magically warm up. If tropical climates or equatorial latitudes intrinsically doomed societies to poverty, the Aztec and Inca empires could never have been the richest, most densely populated civilizations in the Western Hemisphere in 1500.
Crucially, AJR showed that this reversal did not occur in countries that Europeans never colonized (such as non-colonized parts of Asia and Europe). In the uncolonized world, rich places in 1500 remained rich places in 1900. The reversal happened only within the colonized sample, and it occurred precisely during the late 18th and early 19th centuries with the onset of the Industrial Revolution.
Why? Because where indigenous populations were dense and rich, European colonizers found it lucrative to take over existing tax systems and exploit coerced labor. Where land was empty, they had to attract settlers by offering secure land titles and political assemblies.
When industrialization arrived, extractive colonies could not adopt factories: autocrats feared that industrialization would create an educated urban working class that would overthrow them. Settler colonies, with broad property rights and open markets, rapidly adopted steam, rails, and manufacturing.
Even if you throw out the settler mortality instrument entirely, the Reversal of Fortune stands on its own feet. It demonstrated that history had an institutional turning point that geography could never explain.
10. The Real Engine: The Commitment Problem
The second, and perhaps most profound, reason Acemoglu, Johnson, and Robinson won the Nobel Prize is that they were not merely empirical instrument hunters. They were political economy theorists of the highest order.
Throughout the late 1990s and 2000s, Daron Acemoglu and James Robinson developed a unified mathematical theory of institutional emergence, persistence, and transition, culminating in their 2006 masterwork, Economic Origins of Dictatorship and Democracy, and their 2012 bestseller, Why Nations Fail.
For decades, standard neoclassical economics struggled with a simple, naive question: If inclusive institutions and secure property rights make the economic pie so much larger, why don't dictatorial elites simply adopt good institutions, maximize GDP, and tax the resulting wealth?
AJR answered with a brilliant game-theoretic insight: The Dynamic Commitment Problem.
Consider a ruling oligarchy:
- The Elite's Dilemma: If the elite allow secure property rights, free entry, and creative destruction, new merchants, entrepreneurs, and industrial workers will become rich.
- The Credibility Deficit: With their new wealth, the rising merchant class will eventually demand political power. The elite can promise: "Allow us to remain dictators, and we promise never to tax your factories or expropriate your wealth." But that promise is time-inconsistent. Once the factories are built and the investments are sunk, the dictator has every incentive to renege and seize the assets.
- Blocking Progress: Knowing they will be expropriated, entrepreneurs refuse to invest unless the elite surrender political power. But surrendering political power (introducing democracy and independent courts) means the majority might vote to redistribute the elite's hereditary land and wealth. Therefore, the rational choice for the elite is to deliberately block technological innovations and perpetuate extractive institutions to preserve their political monopoly.
This was the theoretical machinery that made AJR's work immortal. They showed why poor countries stay poor: not because their leaders lack economic textbooks or policy advice from the IMF, but because institutional inefficiency is the deliberate equilibrium outcome of a struggle for political survival.
Democratization happens not when elites experience moral enlightenment, but when the disenfranchised masses mobilize a credible revolutionary threat (as in 19th-century Britain or 1918 Sweden). Because the elite's promises of temporary reform are not credible, the only way to avoid the guillotine is to permanently transfer de jure political power by expanding the franchise.
AJR (2001) was not an isolated econometric exercise. It was the empirical front door to an entire theoretical mansion.
11. Epistemic Synthesis: The Vector Field Model
In the philosophy of science, there are two distinct ways to evaluate an empirical paper:
The Measurement Model
A paper is valuable if and only if its estimated coefficient $\hat{\beta} = 0.94$ represents a true, unchanging, structural constant of reality—analogous to measuring the mass of the electron or the speed of light. If the instrument is weak, the data imputed, or the exclusion restriction leaky, the paper is an empirical failure.
The Vector Field Model
A paper is valuable because it alters the force field of an entire scientific discipline. It reframes what questions are permissible, destroys an entrenched, lazy orthodoxy, constructs an arena for dispute, and forces a thousand researchers to invent sharper tools.
By the standards of the Measurement Model, AJR (2001) is a flawed paper. Nobody in development economics today believes that $\hat{\beta} = 0.94$ is an immutable law of nature. Nobody believes that settler mortality operates down a pure, uncontaminated channel devoid of health or human capital spillovers.
Yet the Nobel Prize was entirely justified under the Vector Field Model.
Consider what economics looked like after AJR (2001). By proposing a bold, falsifiable natural experiment, AJR forced the entire discipline to take history, institutions, and path dependence seriously. They liberated development economics from the fatalistic grip of geographic determinism.
Even more remarkably, the very flaws of their cross-country instrument birthed the modern subfield of Historical Political Economy. Because researchers realized that cross-country regressions with 64 observations were inherently vulnerable to weak instruments and multi-channel leaks, they took AJR's core hypothesis—that historical extractive institutions cast enduring shadows—and tested it using high-resolution, within-country micro-natural experiments:
- Melissa Dell (2010): Used a spatial regression discontinuity design across the historical boundary of the mining mita in Peru and Bolivia. She showed that centuries after the forced labor draft ended, households inside the historical mita boundary suffer from 25% lower consumption and stunted road networks, because colonial authorities suppressed land ownership and public goods.
- Nathan Nunn (2008): Combined shipping logbooks and ethnic boundaries to measure the long-run causal impact of the transatlantic slave trade, demonstrating that African regions that suffered the most intensive slave extraction have significantly lower GDP and social trust today.
- Abhijit Banerjee and Lakshmi Iyer (2005): Exploited historical boundaries of British colonial land revenue systems in India, proving that districts where the British assigned proprietary tax collection to predatory landlords (extractive) have significantly lower agricultural investment, literacy, and health today than districts where rights were vested in individual cultivators (inclusive).
- Stelios Michalopoulos and Elias Papaioannou (2013): Examined partitioned ethnic groups sliced across national borders by European colonial cartographers in Africa, demonstrating that pre-colonial institutional centralization matters more for modern economic development than national formal institutions.
Every single one of these landmark papers is a direct intellectual descendant of Acemoglu, Johnson, and Robinson. Without AJR's audacious 2001 paper to serve as the pioneer, none of this subsequent literature would exist in its current form.
In physics, nobody revokes Galileo's place in the pantheon because his rolling-ball experiments on inclined planes lacked friction corrections, or because his telescope had chromatic aberration. Galileo's genius was not that his timing measurements were accurate to four decimal places; his genius was that he proved the solar system was not Ptolemaic, pointed humanity in the right direction, and built the conceptual foundation upon which Newton could stand.
Acemoglu, Johnson, and Robinson's settler mortality instrument was a fragile sledgehammer. It swung hard, shattered the fatalistic consensus that geography was destiny, and cracked open the empirical study of institutional history. The econometric community spent the next twenty years picking up the shards and fashioning them into surgical scalpels.
That is why the Nobel Committee wrote, with full awareness and serene intellectual honesty, that while the number itself should be taken with a grain of salt, the revolution it unleashed changed economics forever.